Effect of the thymidine analogue 5-bromo-2′-deoxyuridine on dictyostelium discoideum development

Abstract Normal morphogenesis of Dictyostelium discoideum is prevented when 5-BUdR is added to growing vegetative amoebac at least one doubling before the onset of differentiation. The mode of action of the analogue on Dictyostelium closely parallels its mode of action on the metazoans.