Major Factors Responsible for Diseases Enhancement: A Review

This paper reviews studies on diseases enhancing factors in human, in a cumulative manner, with special emphasis on changing environmental conditions due to human activities. In present time growing population is responsible for deforestation, urbanization, and excessive exploitation of natural resources which results into drastically changing environmental conditions. Climatic difference, rising temperature leads to global warming which has substantial adverse effect on human health and we become prone to diseases. Abruptly changing environmental conditions support the persistence of highly infectious diseases like Dengue, Malaria, Chikungunya, Tuberculosis etc. Due to ever changing climate in tropical and subtropical countries new sustainable vector species are flourishing. Apart from horizontal gene transfer (HGT) which spreads genetic diversity by moving genes across species boundaries by rapidly introducing newly evolved genes into existing genomes, adaptability to environment among organisms for their survival and development to resist adverse conditions leads to genetic variability through evolution. Failure to combat the diseases with available different re-sources for therapeutical use, including antibiotics and vaccines is the outcome of the modified genetic makeup of organisms. Genomic variability and novelty has made many infectious organisms to evade immune system efficiently and they are not traceable until reach highly viremic stage. Financial, educational, food, shelter and healthcare inequality among people have worsened the situation and causing more damage to poor rather than affluent people around the world.