PROLIFERATIVE RESPONSE TO SEVEN AFFINITY PURIFIED MYCOBACTERIAL ANTIGENS IN EIGHT STRAINS OF INBRED MICE

This study compares the T-cell-stimulating ability of different mycobacterial antigens. The responses to crude culture filtrates and seven affinity-purified antigens were investigated in eight strains of inbred mice. The results demosntrate the significance of the choice of mouse strain in studies of mycobacterial immunology and, furthermore, indicate that when research is conducted to develop new mycobacterial vaccines, it is important to include panels of antigens