Оценка влияния L-орнитина L-аспартата и эмпаглифлозина на физическую работоспособность при экспериментальном стеатогепатите

In the present study, we evaluated the effects of L-ornithine L-aspartate on the physical performance of C57BL/6 mice with experimental non-alcoholic fatty liver disease (NAFLD) induced by a high-caloric “western” diet combined with intraperitoneal carbon tetrachloride injections. Using the forced swim test and triple weight-loaded exhaustive swim test, this model of NAFLD was shown to cause a significant impairment of physical performance and a decrease in physical recovery. L-ornithine L-aspartate was found to significantly improve physical performance and benefit post-exercise recovery in mice with NAFLD.