Harmonization" of donor and recipient tomography in corneal transplantation.

Abstract The applicability of donor and recipient tissue matching in corneal transplantation (“harmonization”) to reduce residual astigmatism after keratoplasty was simulated using Matlab software. The height profile of the donor and recipient corneas was measured using the anterior segment optical coherence tomography (AS-OCT) Casia 2. After best fit of the donor button in the recipient bed the mean height difference as the mismatch, which had to be minimized, was derived from the height profile of the donor and recipient corneal front and back surfaces. The donor button was rotated in the recipient bed to extract the best fit situation where the mean height difference was minimized. After successful simulation, the procedure will be transferred to real measurement data.