Murine monoclonal antibody development.

1. They are extremely pure immunological reagents that can be produced by immunization with a heterogenous antigenic preparation; 2. They are homogenous with respect to affinity and specificity; 3. The specificity of the antibody is directed to a single epitope; 4. The desired MAb can be selected for activity, affinity, and subclass by applying appropriate screening methods; and 5. Virtually unlimited quantities of MAb can be produced.