Biphasic modulation of insulin signaling enables highly efficient hematopoietic differentiation from human pluripotent stem cells
2018
Background
Hematopoietic lineage cells derived from human pluripotent stem cells (hPSCs) hold great promise for the treatment of hematological diseases and providing sufficient cells for immune therapy. However, a simple, cost-effective method to generate large quantities of hematopoietic stem/progenitor cells (HSPCs) is not yet available.
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