A new synthesis of the 3,6-branched hexasaccharide fragment of the cell wall mannan in Candida albicans, corresponding to the antigenic factor 4

In the context of the project dealing with the synthesis and immunological study of the immunodominant fragments of the cell wall mannan in Candida albicans, the hexamannoside fragment corresponding to the antigenic factor 4 was assembled using the scheme [3+2+1]. The yield of the target hexasaccharide with the (α1→3)-glycosidic bond was higher than that obtained according to the previously used assembly scheme [2+2+2].