Optics design and beam dynamics simulation for a VHEE radiobiology beam line at PRAE accelerator

The Platform for Research and Applications with Electrons (PRAE) is a multidisciplinary R&D facility gathering subatomic physics, instrumentation, radiobiology and clinical research around a high-performance electron accelerator with beam energies up to 70 MeV. In this paper we report the complete optics design and performance evaluation of a Very High Energy Electron (VHEE) innovative radiobiology study, in particular by using Grid mini-beam and FLASH methodologies, which could represent a major breakthrough in Radiation Therapy (RT) treatment modality.