Sonochemical synthesis of gold nanoparticles via palm oil fronds extracts for cytotoxicity assay

One of the major focus of scientific community todays is the synthesis of nanoparticles using various bio agents, which are biodegradable for their subsequent bio-application. One pot green synthesis of gold nanoparticles (AuNPs) was successfully achieved using palm oil fronds extracts as stabilizing agent and ultrasound radiation as reducing agent. The functional groups such as OH–, CO – stretch, NH – stretching and other function groups were found to be responsible for stabilizing the AuNPs. The size and morphology of the as-synthesized AuNPs was investigated using HRTEM. The XRD patterns display the peaks of face centred cubic crystal structures at (111), (200), (220), (311) and (222). The cytotoxicity of the bio-synthesized was investigated using human embryonic kidney 293 cells (HEK-293 cells) and breast cancer cell (MCF-7 cells) in vitro study, where more than 50 % of the cells were viable after exposure from 0 mg/ml (negative control) to 1 mg/ml, which indicates the material suitability in future medical application.