Neogenin regulates mitochondrial activity in pre-implantation mouse embryos.

Abstract • Mitochondrial activation signaling pathways are not clearly identified. • Embryonic mitochondria activity is important for a successful pregnancy and live birth. • Neogenin is a multi-functional receptor that contributes to embryo development. • Neogenin as a receptor is related to mitochondrial activation and replication. • Neogenin could activate mitochondria in pre-implantation embryo development.