A Raman Tweezer Study with Single Red Blood Cells for the Diagnosis of Paroxysmal Nocturnal Hemoglobinuria

Seyma Parlatan,Uğur Parlatan,Kaan Batu Soysal,Metban Mastanzade,Murat Ozbalak,Mustafa Nuri Yenerel,Günay Başar,Burcin Unlu

A Raman Tweezer Study with Single Red Blood Cells for the Diagnosis of Paroxysmal Nocturnal Hemoglobinuria

2021

Seyma Parlatan
Uğur Parlatan
Kaan Batu Soysal
Metban Mastanzade
Murat Ozbalak
Mustafa Nuri Yenerel
Günay Başar
Burcin Unlu

The surface structure of individual erythrocytes changes in the state of paroxysmal nocturnal hemoglobinuria. We proposed a diagnostic model by Raman tweezers which provided optical immobilization and chemical interrogation

Keywords:

Paroxysmal nocturnal hemoglobinuria
Raman spectroscopy
laser beams
Optical tweezers
surface structure
Materials science
Tweezers
Nuclear magnetic resonance
diagnostic model

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