Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner

Sandeep Sharma,Erik Chorell,Pär Steneberg,Emma Vernersson-Lindahl,Helena Edlund,Pernilla Wittung-Stafshede

Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner

2015

Sandeep Sharma
Erik Chorell
Pär Steneberg
Emma Vernersson-Lindahl
Helena Edlund
Pernilla Wittung-Stafshede

The insulin-degrading enzyme (IDE) degrades amyloidogenic proteins such as Amyloid β (Aβ) and Islet Amyloid Polypeptide (IAPP), i.e. peptides associated with Alzheimer's disease and type 2 diabetes ...

Keywords:

Synuclein
Enzyme
Insulysin
Alpha-synuclein
Insulin-degrading enzyme
Biochemistry
Islet
Amyloid
Fibril
Chemistry
Protease
In vivo
In vitro

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations