CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF Cinnamomum zeylanicum Blume ESSENTIAL OIL ON MULTI-DRUG RESISTANT Acinetobacter spp. strains

The genus Acinetobacter comprises a group of Gram-negative bacteria and non- fermenters of glucose that are important nosocomial pathogens, many of which being resistant to many antimicrobial agents. Studies on the antibacterial activity of new products have been conducted, including the essential oils. The essential oil analysis resulted in the identification of five components with eugenol as the major component. The essential oil at 625 µg/ml concentration produced inhibition on the growth of 71% strains of Acinetobacter and the MBC was established as 1250 µg/mL. It was observed from the time kill experiment that the essential oil of Cinnamomum zeylanicum has concentration-dependent bactericidal activity. The results of this study have shown the antibacterial potential of the essential oil and may lead to future researches on this essential oil or your chemical constituents, aiming its possible clinical application in the treatment of infections caused by multi drug resistant Acinetobacter species.