Iridium-Catalyzed Enantioselective Allylation of ArylEnamides and Enecarbamates

Aromatic enamide and enecarbamate as a novel type of nucleophile in the asymmetric allylation of branched, racemic allylic alcohols to give homoallylic ketones has been described. Enabled by Carreira’s chiral Ir (P, olefin) complex, the reactions proceed in good yields with excellent enantioselectivities.