Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice
2015
Fsp27 mediates ‘fusion’ of lipid droplets in mouse adipose tissue. Here, the authors investigate the physiological consequences of loss of Fsp27 in three different mouse models of ‘energetic overload’, and observe hepatic steatosis and insulin resistance but reduced adipose tissue inflammation.
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