Efficacy of leaves extract of Acacia nilotica against Pseudomonas aeruginosa with reference to Disc diffusion method

2014 
In the past few decades, the search for new anti-infection agents has occupied many research groups in the field of ethno pharmacology. The medicinal plants serve as, potential antimicrobial crude drugs as well as a source for natural compounds that act as new anti-infection agents. The use of plants by man came about through observation of their definite effects on animals and man. Increasing number of plants are been screened for their anti-microbial activity day by day. According to World Health Organization (WHO) more than 80% of the world's population relies on traditional medicine for their primary healthcare needs. The medicinal plant used for current study Acacia nilotica is mostly indicated to be abundant and rare. The methanol, chloroform, hexane and petroleum ether extracts of Acacia nilotica was tested for its efficacy against gram-negative bacteria: Pseudomonas aeruginosa, using disc diffusion method. The result demonstrated that the methanol extract is more efficient than the other solvent extracts in suppressing the bacterial growth in the study.
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