Developmental sex disorders: brief review on current ethical aspects.

: Among the urgent issues of the current medical ethics is the patient-doctor relationship. The care of patients with disorders of sexual differentiation (DSD) is an example of this relationship and its clinical ethical aspects. For centuries differences in gender have captured our attention. We illustrate examples of DSD patients. The standard of care based on previously accepted hypothesis is discussed. Adult population with DSD provided evidence which challenged the way we used to care these individuals. The latter served as an opportunity to revised and develop the current standard of care for individuals with DSD.