Multiscale Simulation of Bioreactor Design and In Vitro Conditions

Tissue grafts obtained from tissue engineering techniques can be developed with the application of cells in a scaffold within a bioreactor. In this chapter we present a multiscale method to simulate a bioreactor design that can adapt to the personalized tissue sought. It includes personalization of the bioreactor design but also personalization of the in vitro conditions. As the research area is going further and the computational possibilities as well, tools must be developed to design patient’s cell-specific pair of scaffold and bioreactor, as a virtual physiological human cell tool.