MiR-139-5p is associated with poor prognosis and regulates glycolysis by repressing PKM2 in gallbladder carcinoma

2018 
Objectives Gallbladder carcinoma (GBC) is the most highly aggressive cancer of biliary tract, but effective therapeutics are lacking. Emerging evidence has unveiled that miR‐139‐5p is aberrantly downregulated in cancers, including GBC. However, the functions and mechanisms of miR‐139‐5p in GBC remain unclear.
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