Field-amplified stacking injection-capillary electrophoresis for quantitative analysis of fluoride released from dental composite

The release of fluoride is an important factor in evaluating a composite restorative material due to its anticariogenic effect. Field amplified stacking injection in capillary electrophoresis was studied to determine the concentration of fluoride released from dental restorative materials. A detection limit of 20 ng/mL was obtained with good reproducibility (relative standard deviation <4%). The method was applied to the analysis of fluoride released from four different types of commercially available dental composites over 28 days. Results showed that field-amplified stacking injection-capillary electrophoresis was effective in monitoring the fluoride release process and product quality of different kinds of restorative materials.