Status atual e perspectiva futura de cultura de tecido ovariano canino e felino

The culture of ovarian follicles is an important tool for understanding of the mechanisms controlling follicle development and differentiation of its oocyte. The benefit from recovering developmentally competent oocytes from small, immature follicles (primordial, primary, secondary and early antral) also would be significant, ranging from rescue of genomes from endangered species to preserving fertility in female cancer survivors. To-date, live offspring from cultured primordial follicles has occurred only in the mouse. Progress in larger, more complex species has been limited because these animal models have longer durations of natural folliculogenesis, thereby requiring more culture time to generate fully grown follicles and oocytes. In this presentation, we highlight current status of this topic for domestic carnivores (i.e., dogs and cats) as well as future research priorities.