Inhibition of multi-drug resistance of ovarian carcinoma by small interfering RNA targeting to MRP2 gene

Jia-jia Ma,Bi Liang Chen,Xiao-yan Xin

Inhibition of multi-drug resistance of ovarian carcinoma by small interfering RNA targeting to MRP2 gene

2009

Jia-jia Ma
Bi Liang Chen
Xiao-yan Xin

Aims To investigate the inhibiting mechanism of multi-drug resistance (MDR) using expression vectors of short hairpin RNA (shRNA) in a MDR human ovarian cancer cell line (A2780/cp70).

Keywords:

Drug resistance
Gene
Small hairpin RNA
Expression vector
Small interfering RNA
Genetic enhancement
Multiple drug resistance
RNA silencing
Biology
Molecular biology
ovarian carcinoma

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