Cardiac ankyrin repeat protein attenuates cardiac hypertrophy by inhibition of ERK1/2 and TGF-β signaling pathways.

Yao Song,Jialin Xu,Yanfeng Li,Chunshi Jia,Xiaowei Ma,Lei Zhang,Xiaojie Xie,Yong Zhang,Xiang Gao,Zhang Y,Dahai Zhu

Cardiac ankyrin repeat protein attenuates cardiac hypertrophy by inhibition of ERK1/2 and TGF-β signaling pathways.

2012

Yao Song
Jialin Xu
Yanfeng Li
Chunshi Jia
Xiaowei Ma
Lei Zhang
Xiaojie Xie
Yong Zhang
Xiang Gao
Zhang Y
Dahai Zhu

Aims It has been reported that cardiac ankyrin repeat protein is associated with heart development and diseases. This study is aimed to investigate the role of CARP in heart hypertrophy in vivo.

Keywords:

Nuclear protein
Phosphorylation
Fibrosis
Cell biology
Signal transduction
Transforming growth factor beta
Transforming growth factor
Heart development
Internal medicine
Endocrinology
Biology
Muscle hypertrophy
ANKRD1
Phenylephrine
MAPK/ERK pathway
Genetically modified mouse
Pressure overload
Carp

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