PHARMACEUTICO ANALYTICAL STANDARDIZATION OF RASA BHASMA PREPARED AS PER RASA MANJARI BY USING BHUDHARA YANTRA METHOD

Metals and minerals are being used in Ayurveda pharmaceutics and therapeutics since a very long period. Herbomineral formulations or Rasoushadhi are considered as more potent and quick acting. Rasa (mercury) is given prime importancein Rasashastra owing to its remarkable therapeutic potential. However, Rasa is to be utilized in any of the three forms i.e; MritaParada, BaddhaParada and MoorchithaParada.MrutaParada refers to ParadaBhasma which is claimed to have immense therapeutic potential and also helps to improve longevity. Rasa Bhasma or ParadaBhasma is a formulation mentioned in various text books of Rasashastraviz.,RasaRatnaSamuchchaya, Rasa Raja Sundara, Yoga Ratnakara, Bhavaprakasha, SharangadharaSamhita, Rasa PrakashaSudhakara, Vaidya Yoga Tarangini, BrihatNighantu, Rasa Manjari, Rasa Tarangini etc. But nowadays practically Rasa Bhasma is not being prepared due to the difficulty in the process and heat sensitivity of Parada. Here, an attempt was made to prepare Rasa Bhasma by following the reference of Rasa Manjari with due importance to Standard Operative Procedure. Three batches were prepared to standardize the process. Prepared Bhasma was tested following organoleptic, classical bhasmapareekshaand physico-chemical parameters. Advanced instrumental methods like SEM-EDAX, XRD, DLSand ICP-OESetc were followed to develop analytical standards.