Considerations for the Intersection of Sedation and Marijuana

The large and increasing prevalence of cannabis use obligates practitioners to be familiar with the pharmacology and clinical ramifications of cannabinoids. Childhood exposure to cannabis spans medical therapy to accidental ingestion and self-experimentation. Although tetrahydrocannabinol is the most well-characterized cannabinoid, use of cannabidiol has dramatically increased in recent years. A branded form of cannabidiol has received approval for use in certain refractory childhood seizure disorders. Cannabis-associated accidental intoxication, minor trauma, and medication side effects can result in the urgent medical evaluation of minors.