Positive modulation of a Cys-loop acetylcholine receptor by an auxiliary transmembrane subunit

In this paper, Bessereau and colleagues identify MOLO-1 as an auxiliary subunit for levamisole-sensitive acetylcholine receptors (L-AChRs) present at the neuromuscular junction of C. elegans. MOLO-1 is the first auxiliary subunit ever found for a member of the Cys-loop receptor superfamily.