Pharmacokinetic Interaction between Indinavir and Darunavir with Low-Dose Ritonavir in Healthy Volunteers

Vanitha Sekar,Eric Lefebvre,Tine De Marez,Martine De Pauw,Els De Paepe,Tony Vangeneugden,Richard M. W. Hoetelmans

Pharmacokinetic Interaction between Indinavir and Darunavir with Low-Dose Ritonavir in Healthy Volunteers

2010

Vanitha Sekar
Eric Lefebvre
Tine De Marez
Martine De Pauw
Els De Paepe
Tony Vangeneugden
Richard M. W. Hoetelmans

Objective: To investigate the potential for a pharmacokinetic interaction between darunavir (DRV, TMC114, Prezista®), indinavir (IDV, Crixivan®) and low-dose ritonavir (RTV, Norvir®

Keywords:

Ritonavir
Darunavir
Virology
Indinavir
Area under the curve
Biology
Pharmacokinetics
healthy volunteers
pharmacokinetic interaction
low dose
Pharmacology

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