INTERACTIONS OF THE NERVOUS AND IMMUNE SYSTEMS IN HEALTH AND DISEASE

The historical aspects of formation of immunophysiology as a sciences as well as the review of modern studies of interactions between nervous and immune systems in health and disease are reviewed in the article. The recent data describing the CNS reactions to antigen stimuli of different nature and possibility of involvement in these reactions of neurons of different ergicity, in particular, orexin-containing hypothalamic neurons are cited. Besides, one of the possible hypotheses about information transduction pathways from immune system to the nervous is observed in the article.