−1H and −13C NMR Study of C‐16 OYL and C‐17 Acyl Vinblastine Derivatives at 300 MHz Using 2‐D NMR Experiments
2010
In the present study we describe: (1) the −13C NMR study of two compounds resulting from the amidation of the ester at C-16 of 17-deacetyl-vinblastine and (2) the −1H and −13C NMR study of one compound resulting from the acylation (or esterification) at C-17 of vinblastine. For the assignment of the −13C NMR resonances, DEPT and −13C, −1H-heteronuclear shift correlated experiments were performed.
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