Life trajectories towards suicide: developmental role and specificities of adolescence

Objective: Considering that adolescence is a crucial period of allostatic maturation, we aimed at testing whether it represents a breakpoint in adversity trajectories to suicide and, relatedly, whether life trajectories of adolescents who died by suicide differ from those of adult counterparts. Method: In 303 individuals who died by suicide, a panel of experts derived longitudinal burden of adversity ratings from extensive clinical interviews conducted with informants. Piecewise Joint Latent Class Models allowed to identify patterns of adversity trajectories and test the introduction of breakpoints in life-paths. The classes inferred from the optimal model were compared in terms of socio-demographics, psychopathology and nature of experienced events. Results: The most accurate model derived 2 trajectory patterns with a breakpoint in early adolescence. In the first class (n = 43 individuals), the burden of adversity increased steadily from birth to death, which occurred on average at 23 (SE = 1.29). In the second class (n = 259), where individuals died on average at 43 years (SE = 0.96), the burden of adversity followed a similar trajectory during infancy but stabilized between ages 10 and 14 years and rebounded at about 25. The classes differed in terms of childhood family stability, occurrence of dependent events, distal exposure to suicide and intra-family sexual victimization. Conclusion: Although subject to inherent limitations of the retrospective designs, our results encourage clinicians and researchers to pay greater attention to the diathetic maturation processes occurring during adolescence when considering suicidal behaviors in young people.