Chemical constitutes from endophytic Streptomyces sp. W5 isolated from Trewia nudiflora L.

Strain W5 was isolated from stem of Trewia nudiflora L. and identified as a member of Streptomyces according to its 16S rDNA partial sequence. From extracts of fermentation medium of W5, a new γ-butyrolactone (1), together with nine known compounds [2-methyl-2,5-bornandiol (2), dimeric dinactin (3), (R)-2-((2R,5S)-tetrahydro-5-(2-oxopropyl)furan-2-yl)propanoic acid (4), 2-(5-(2-acetoxypropyl)-tetrahydrofuran-2-yl)propanoic acid (5/6), (±)-homononactic acid (7/8), (±)-nonactic acid (9/10)] was isolated. Their structures were elucidated on the basis of extensive spectroscopic data.