Bioelectrical Signal Analysis of Mouse Cardiomyocyte Culture recorded on Thin-Film-Transistor Sensor Arrays

The dynamical property of the heart bioelectrical system is closely associated with cardiac diseases. There is thus a growing interest in the development of system analysis for studying the cardiac signaling network. In this article, the electrical potentials of cardiac muscle cells have been measured on an array of microelectrodes using the Thin-Film-Transistor (TFT) technology, and electrophysiological data were analyzed. This study shows the possibility of obtaining and accurately analyzing extracellular signals measured on TFT arrays.