Copper(II)-catalyzed cascade approach for the synthesis of pyrrolo[2,1-f][1,2,4]triazine-fused isoquinolines
2014
We report herein a one-pot copper(II)-catalyzed coupling-cyclization leading to small molecules based on a novel structural motif, i.e. the pyrrolo[2,1-f][1,2,4]triazine moiety fused with an isoquinoline ring. The reaction is easy to perform in good to excellent yields with high atom economy and exhibits a broad substrate scope.
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