Complex Segregation Analysis of Thyroid Autoantibodies: Are They Inherited as an Autosomal Dominant Trait?

David I. W. Phillips,Denis C. Shields,J.M. Dugoujon,L. Prentice,Peter McGuffin,B. Rees Smith

Complex Segregation Analysis of Thyroid Autoantibodies: Are They Inherited as an Autosomal Dominant Trait?

1993

David I. W. Phillips
Denis C. Shields
J.M. Dugoujon
L. Prentice
Peter McGuffin
B. Rees Smith

The presence of circulating autoantibodies (Abs) to the thyroid antigens thyroid peroxidase (TPO) and thyroglobulin (Tg) is a marker for autoimmune thyroid disease. Recent studies have suggested that

Keywords:

Thyroid peroxidase
Thyroid
Genetics
Biology
Autoantibody
Autoimmune disease
Anti-thyroid autoantibodies
Complex segregation analysis
Dominance (genetics)
Thyroglobulin
Immunology
Internal medicine
Endocrinology
autosomal dominant trait

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