Evaluation of antimicrobial activities of powdered cuttlebone against Klebsiella oxytoca, Staphylococcus aureus, and Aspergillus flavus
2021
Background: The presence of medicines in the environment is considered as a serious threat to the
human health. The entrance of these substances into the water sources causes soil pollution, which
eventually leads to the environmental pollution and it creates some problems for the public health. Also,
increasing antibiotic resistant bacteria has attracted the attention of researchers to the use of natural
resources such as marine products, for producing new antibiotics. The aim of this study was to evaluate
antimicrobial activities of powdered cuttlebone against Klebsiella oxytoca, Staphylococcus aureus, and
Aspergillus flavus.
Methods: At first, cuttlebones were washed, dried, and powdered. Then, the powdered cuttlebone
was characterized. In the next step, its antimicrobial activities were evaluated using agar well diffusion
technique, and minimum inhibitory concentration (MIC) was calculated.
Results: The powdered cuttlebone was found to be effective against K. oxytoca (24 mm, MIC: 10-1
mg/mL), but no antimicrobial response was found against S. aureus. Also, the powdered cuttlebone
antifungal activity and MIC against A. flavus were recorded 23 mm and 10-1 mg/mL, respectively.
Conclusion: The obtained results suggest antimicrobial activities of powdered cuttlebone, which are
concentration dependent. Furthermore, cuttlebone can be used as an accessible natural source to
provide novel, low cost, and safe antimicrobial agents.
Keywords: Antibacterial activity, Antibiotics, Antifungal activity, Marine products, Minimum inhibitory
concentration
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
0
References
0
Citations
NaN
KQI