Union members specific for the beta transforming growth human factor; materials and methods.

MEMBERS OF UNION SPECIFIC UNDERSTANDING DOMAINS antigen binding human antibodies specific for Transforming Growth Factor HUMAN BETA (TGF BE) specifically bind to isoforms TGF BE 2 AND TGF BE 1 OR BOTH, preferentially IN COMPARISON WITH TGF BE 3. UNION MEMBERS SPECIFIC can be isolated and used in the treatment of diseases, particularly fibrotic DISEASES AND ALSO INMUNO / inflammatory diseases. THERAPEUTIC UTILITY MODEL IS SHOWN IN VITRO USING AND IN VIVO. SE BRINGS THE FULL SEQUENCE UNION AND INFORMATION, INCLUDING INFORMATION FOR STRINGS Epitope UNION MEMBER OF SPECIFIC particularly advantageous JOINS active form of TGF BE 2, neutralizing its activity, but not attached to the latent form.