Design, Synthesis and Cytotoxic Evaluation of 4-Anilinoquinazoline– triazole–AZT Hybrids as Anticancer Agents

Le Nhat Thuy Giang,Nguyen Thi Nga,Dinh Thuy Van,Dang Thi Tuyet Anh,Hoang Thi Phuong,Nguyen Ha Thanh,Le Thi Tu Anh,Vu Quoc Trung,Nguyen Van Tuyen,Phan Van Kiem

Design, Synthesis and Cytotoxic Evaluation of 4-Anilinoquinazoline– triazole–AZT Hybrids as Anticancer Agents

2018

Le Nhat Thuy Giang
Nguyen Thi Nga
Dinh Thuy Van
Dang Thi Tuyet Anh
Hoang Thi Phuong
Nguyen Ha Thanh
Le Thi Tu Anh
Vu Quoc Trung
Nguyen Van Tuyen
Phan Van Kiem

A series of 4-anilinoquinazoline–triazole–AZT hybrids were designed and synthesized as anticancer agents. Their cytotoxic potential has been evaluated by means of a micro-dilution assay against thr...

Keywords:

Biology
Triazole
Cytotoxic T cell
Biochemistry
design synthesis

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