“Click-chemical” modification of cellulose acetate nanofibers: a versatile platform for biofunctionalization

Cellulose acetate nanofibers have attracted considerable interest in the biomedical sciences, but lack convenient biofunctionalization methods. In this work the “sulfur(vi)–fluoride exchange reaction”, a new type of click chemistry, is used for the first time to overcome many of the difficulties previously encountered and provide a platform for biofunctionalization generally.