The characteristics of opioid receptors distributed in the neurons of habenula

Aim: To explore the types of receptors distributed in MHb and LHb. Methods: Recording the currents of potassium channels in Hb neurons isolated from the rats 10～15 days after birth. To distinguish the types of receptors distributed in MHb and LHb by using the agonists of μ receptor DAMGO, and σ receptor DPDPE. Results: Two types of current of K + channels were recorded, the transient rectifier and delayed rectifier potassium channels. DAMGO or DPDPE increased the intensity of current of K + channels. Conclusion: In MHb there was a higher density of σ receptor, and in LHb a higher density of μ receptor distributed.