Cyclic homopentapeptides 3. Synthetic modifications to the capreomycins and tuberactinomycins: Compounds with activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci

Robert Gerald Linde,N.C. Birsner,R.Y. Chandrasekaran,Joanna Clancy,R.J. Howe,J.P. Lyssikatos,C.P. MacLelland,Thomas V. Magee,J.W. Petitpas,J.P. Rainville,W.-G. Su,C.B. Vu,David A. Whipple

Cyclic homopentapeptides 3. Synthetic modifications to the capreomycins and tuberactinomycins: Compounds with activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci

1997

Robert Gerald Linde
N.C. Birsner
R.Y. Chandrasekaran
Joanna Clancy
R.J. Howe
J.P. Lyssikatos
C.P. MacLelland
Thomas V. Magee
J.W. Petitpas
J.P. Rainville
W.-G. Su
C.B. Vu
David A. Whipple

Abstract Modification and replacement of the β-lysine side chain of capreomycin and tuberactinomycin cyclic pentapeptide derivatives resulted in compounds with good antibacterial potency against multidrug-resistant pathogens.

Keywords:

Meticillin
Methicillin-resistant Staphylococcus aureus
Pentapeptide repeat
Staphylococcus aureus
Cyclic peptide
Vancomycin
Chemistry
Biochemistry
Capreomycin
Antibiotics
antibacterial agent

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations