Dendritic cell-mediated survival signals in Eμ- Myc B-cell lymphoma depend on the transcription factor C/EBPβ

Dendritic cells (DC) are known to promote cancer progression by suppressing antitumor immunity. Here, Rehm et al. describe a mechanism whereby lymphoma cells induce C/EBPβ activation in DCs, which in turn secrete cytokines that support the proliferation and survival of lymphoma cells.