O-069 Effect of sperm DNA fragmentation on reproductive outcome with donated oocyte cycles

(3.50-6.07) (p < 0.01) and the s-progesterone (ng/mL) levels were D0: 0.72 (0.58-0.89), D50: 1.03 (0.79-1.34), D100: 0.92 (0.79-1.08) and D150: 1.17 (0.82-1.67) (p = 0.03). S-estradiol will be presented later. The patients receiv- ing hCG supplementation were stratified by 33% and 66% percentiles into three groups according to the level of s-hCG on Day 6 of stimulation: 0.5-3.5 IU/L (n = 16), 3.5-8.0 IU/L (n = 14) and 8.0- IU/L (n = 14). The mean number of top-quality embryos in the three groups was 0.5 ± 0.9, 1.1 ± 1.8 and 1.5 ± 1.5, respectively (p = 0.03). The ongoing pregnancy rates per started cycle were 31%, 21% and 29% (p = 0.83). Conclusion: Supplementation with hCG from the first day of stimulation may increase the number of top-quality embryos; even doses up to 150 IU/day are consistent with a high proportion of top-quality embryos and good pregnancy rates. In terms of top-quality embryos, doses from 100 to 150 IU/day of hCG may be optimal, but a proportion of patients with these doses have increased progesterone levels on the last days of stimulation.