Dehydrogenase Binding Sites Abolish the "Dark" Fraction of NADH: Implication for Metabolic Sensing Via FLIM.

Simin Cao,Haoyang Li,Yangyi Liu,Mengyu Wang,Mengjie Zhang,Sanjun Zhang,Jinquan Chen,Jianhua Xu,Jay R. Knutson,Ludwig Brand

Dehydrogenase Binding Sites Abolish the "Dark" Fraction of NADH: Implication for Metabolic Sensing Via FLIM.

2020

Simin Cao
Haoyang Li
Yangyi Liu
Mengyu Wang
Mengjie Zhang
Sanjun Zhang
Jinquan Chen
Jianhua Xu
Jay R. Knutson
Ludwig Brand

The fluorescence of dinucleotide NADH has been exploited for decades to determine the redox state of cells and tissues in vivo and vitro. Particularly, nanosecond (ns) fluorescence lifetime imaging...

Keywords:

Fluorescence-lifetime imaging microscopy
Photochemistry
Fluorescence
Chemistry
Redox
Dehydrogenase
Nanosecond
In vitro
Biophysics
In vivo
Binding site

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