Gefitinib loaded nanostructured lipid carriers: characterization, evaluation and anti-human colon cancer activity in vitro.

Hafiz A. Makeen,Syam Mohan,Mohamed Ahmed Al-Kasim,Ibraheem M. Attafi,Rayan A. Ahmed,Nabeel Kashan Syed,Muhammad Hadi Sultan,Mohammed Al Bratty,Hassan A. Alhazmi,Mohammed M. Safhi,Raisuddin Ali,M. Intakhab Alam

Gefitinib loaded nanostructured lipid carriers: characterization, evaluation and anti-human colon cancer activity in vitro.

2020

Hafiz A. Makeen
Syam Mohan
Mohamed Ahmed Al-Kasim
Ibraheem M. Attafi
Rayan A. Ahmed
Nabeel Kashan Syed
Muhammad Hadi Sultan
Mohammed Al Bratty
Hassan A. Alhazmi
Mohammed M. Safhi
Raisuddin Ali
M. Intakhab Alam

NLC containing Gefitinib (NANOGEF) was prepared using stearic acid, sesame oil and surfactants (sodium lauryl sulfate and tween 80). NANOGEFs were evaluated for particle size, polydispersity index ...

Keywords:

Stearic acid
In vitro
Sulfate
Sodium
Particle size
Chromatography
Gefitinib
Materials science
Colorectal cancer
MTT assay

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