Testosterone secretion in mouse Leydig cells decreasing induced by Radiofrequency electromagnetic radiation

Radiofrequency (RF) electromagnetic radiation (EMR) is non-ionizing radiation with frequencies in the range from about 10 MHz to 300 GHz that directly influences on human health[1], [2]. The RF-EMR field produced by cellular phones is mainly at the frequencies of 850 to 2100 MHz. The studies of RF-EMR on testis function have mostly been performed in vivo level to evaluate gross effects on fertility or testis function, but have not given insight into the effects of this radiation in vitro level. Leydig cells are the interstitial testis cells with a crucial role for regulating spermatogenesis and male reproductive function, which could secrete 95% of the testosterone for the male.