KCl Depolarization Increases HIF-1 Transcriptional Activity via the Calcium-Independent Pathway in SGC7901 Gastric Cancer Cells

Mei Lan,Yongquan Shi,Li Sun,Lili Liu,Xueyan Guo,Yuanyuan Lu,Jun Wang,Jie Liang,Daiming Fan

KCl Depolarization Increases HIF-1 Transcriptional Activity via the Calcium-Independent Pathway in SGC7901 Gastric Cancer Cells

2007

Mei Lan
Yongquan Shi
Li Sun
Lili Liu
Xueyan Guo
Yuanyuan Lu
Jun Wang
Jie Liang
Daiming Fan

Background: Hypoxia-inducible factor 1α (HIF-1α) has been reported to be expressed aberrantly in gastric cancer cells. Stability and transactivation of HIF-1 were associated with th

Keywords:

Transactivation
Cancer research
Calcium
Cancer cell
Molecular biology
Reporter gene
Calcium in biology
Hypoxia-inducible factors
Hypoxia-Inducible Factor 1
Depolarization
Biology
calcium independent
Potassium
transcriptional activity
kcl depolarization

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