LDL Receptor's β-Propeller Displaces LDL
2002
The low density lipoprotein receptor (LDLR) binds to lipoprotein extracellularly and releases it in the endosome. In his Perspective,
Innerarity
discusses new structural work (Rudenko et al .) that shows that an interdomain interaction that occurs at low pH likely displaces ligand from the receptor in the endosome.
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