Tetramethylguanidine-functionalized silica-coated iron oxide magnetic nanoparticles catalyzed one-pot three-component synthesis of furanone derivatives

Tetramethylguanidine-functionalized silica-coated iron oxide magnetic nanoparticles as a productive and reusable catalyst have been applied for the one-pot three-component synthesis of furanone derivatives (4a–o). In addition to the characterization of all products by FT-IR, $$^{1}\hbox {HNMR}$$ and $$^{13}\hbox {CNMR}$$ spectroscopy, single-crystal X-ray analysis of ethyl 5-oxo-2-phenyl-4-(phenylamino)-2,5-dihydrofuran-3-carboxylate product has been made. Easy recrystallization and good-to-excellent yields (81–92%) of furanone derivatives are notable characteristics of this procedure. The catalyst identification was performed using FT-IR, XRD, SEM, TEM and TGA techniques. It is worth noting that the nanocatalyst can be recycled with an external magnet and reused for several times. SYNOPSIS In this procedure, tetramethylguanidine-functionalized silica-coated iron oxide magnetic nanoparticles $$(\hbox {Fe}_{3}\hbox {O}_{4}\hbox {-TMG})$$ has been employed as an efficient, eco-friendly and reusable catalyst for one-pot three-component synthesis of furanone derivatives in a green solvent at $$40\,^{\circ }\hbox {C}$$ . The use of magnetic nanocatalyst is the superior feature of this method.