SECRETORY MENINGIOMA A CONVENTIONAL HISTOCHEMICAL STUDY OF SIX CASES

SUMMARY: Six meningiomas with abundant hyaline inclusions (pseudopsammoma bodies) were studied in means of a panel of conventional histochemistry. In all six cases. the inclusions were PAS-positive, diastase resistant and stained picrophilic (yellow-bright orange) with van Gieson. Negative staining was obtained by von Kossa. Con­ go red and Gomori's reticulin. A remarkable pericytic proliferation around the vessel wall was found in five cases. It is concluded that secretory meningioma is a distinct type of meningioma. It shows characteristic light­ microscopic. ultrastructural. and immunohistochemical features of epithelial and secretory differentiation.